Which of the following is true regarding cytokines in the context of autoimmune diseases?

Cytokines play a crucial role in the immune system, acting as signaling molecules that modulate immune responses. In the context of autoimmune diseases, some cytokines promote inflammation and contribute to the dysregulation of the immune system, leading to the attack on self-tissues. This characteristic makes them significant targets for therapeutic intervention.

Monoclonal antibodies can be designed to specifically inhibit certain cytokines, reducing their activity and therefore mitigating the inflammatory responses associated with autoimmune diseases. This is a common approach in treatments for conditions like rheumatoid arthritis or psoriasis, where neutralizing specific pro-inflammatory cytokines can alleviate symptoms and prevent tissue damage.

While cytokines are produced by many different types of cells, particularly those of the immune system, they are not exclusively produced by B cells, nor do they lack a role in immune responses. Thus, the ability to inhibit cytokines with monoclonal antibodies highlights their importance in managing autoimmune diseases effectively.